Evaluation of Von Willbrand factor antigen level in severely affected Covid 19 patients
Author(s): Hala Othman Hassan and Subh Salim Almudallal
Abstract: Background: Severely affected COVID-19 cases with respiratory rate > 30 cycle/minute, pneumonia features and oxygen saturation < 90% may have high VWF due to endothelial cell damage.
Aims of the study: Evaluation of Von Willbrand Factors antigen levels. Finding correlations among (VWF), D dimer and oxygen saturation.
Methods: This cross sectional study was conducted on 50 PCR positive patients were severely affected and admitted to hospitals (Al-Imamain Kadhimian medical city, IBN AL-Khateeb hospital and Dar Al Salam 1field hospital) from January till May 2021. The leftover of plasma samples anticoagulated with trisodium citrate were used for evaluation of VWF: Ag by VIDAS system using VWF kit with ELFA technique. Other parameters were taken from patients files.
Results: The study included 33 males and 17 females with age range of (34-86) years. Mean of VWF, D dimer were high. Oxygen saturation was significantly low and inversely correlated with VWF. There were statistically significant correlations (P Value < 0.05) between VWF and D dimer.
Conclusions: Von Willbrand Factor level was elevated in all patient SD, elevated VWF correlated with elevated D dimer and inversely with oxygen saturation.
DOI: 10.22271/27069567.2024.v6.i2a.547Pages: 08-11 | Views: 320 | Downloads: 128Download Full Article: Click Here
How to cite this article:
Hala Othman Hassan, Subh Salim Almudallal.
Evaluation of Von Willbrand factor antigen level in severely affected Covid 19 patients. Int J Adv Res Med 2024;6(2):08-11. DOI:
10.22271/27069567.2024.v6.i2a.547