2021, Vol. 3, Issue 2, Part I

Aim: To evaluate serum uric acid level correlation in a patient of CKD with or without metabolic syndrome.

Material and Method: The present prospective observational study was conducted in the department of Medicine at Chattrapati Shivaji Subharti Hospital from 2019 to 2021. The study group comprised of 100 patients, suffering from CKD. Metabolic syndrome was assessed according to International Diabetic Federation. Uric acid was estimated using Uricase method.

Results: Out of 100 CKD subjects, 63 were suffering from metabolic syndrome while 37 were free from metabolic syndrome. Maximum subjects were from the age group of >60 years (45%) followed by 51-60 years (37%). Diabetes and hypertension was revealed among 73.02%, 80.95% and 48.65%, 59.46% of the subjects with and without metabolic syndrome respectively. Hyperuricemia was noted among 53.97% and 35.13% of the subjects with and without metabolic syndrome respectively. Mean serum uric acid (mg/dl) in subjects with metabolic syndrome and without metabolic syndrome was 6.64±1.58 and 6.09±1.16 respectively with statistically significant difference as p<0.05.

Conclusion: The above study shows that serum uric acid levels are significantly elevated in CKD patients with metabolic syndrome. The association of elevated levels of serum uric acid was seen with all the components of metabolic syndrome.