2021, Vol. 3, Issue 2, Part D

Material and methods: A 5 months case-control study was carried out at Dhawan Hospital in Ludhiana, Punjab, India, at the request of the researchers. A total of 240 volunteers participated in the study, with 120 type 2 diabetes patients serving as case participants (Group A) and 120 healthy volunteers serving as control participants (Group B). Laboratory testing on a regular basis CBC, FBS, RBS, PP2BS, haemoglobin A1C, blood urea, serum creatinine, lipid profile, urine albumin, and Vitamin D3 levels were all measured using conventional techniques at the institute's central laboratory, according to the guidelines.

Results: When comparing groups A and B, the mean age of group A (case) was 51.42 9.25 years, while the mean age of group B (control) was 50.12 10.18 years. The prevalence of low vitamin D levels in the healthy population was just 19.2 percent, while the prevalence in the diabetic population was 84.2 percent. Vitamin D levels were found to be sufficient, insufficient, and deficient in 18.51 percent, 61.11 percent, and 16.67 percent, respectively, in patients with controlled diabetes according to HbA1C criteria, but only 10.60 percent, 68.18 percent, and 24.24 percent in patients with uncontrolled diabetes, according to the same criteria. In contrast to diabetic patients with managed condition, a higher proportion of diabetic patients with uncontrolled state (24.24 percent) had overt vitamin D insufficiency (16.67 percent). There is a statistically significant relationship between the maintenance of euglycemia and the degree of Vitamin D deficiency in diabetic patients, as shown by a p value less than 0.05.

Conclusion: All patients with type-2 diabetes should have their vitamin D levels checked, and those who are found to have insufficiency or shortage of vitamin D should be prescribed vitamin D supplements. In order to avoid vitamin D insufficiency, it is also necessary to maintain tight control over one's diabetic condition.