2021, Vol. 3, Issue 1, Part I

Background: This randomised, double-blind, prospective research compares the effects of lignocaine with dexmedetomidine on sensory and motor block onset time, intraoperative sedation, tourniquet discomfort, and postoperative analgesia in patients undergoing intravenous regional anaesthetic.

Methods: The Department of Aneasthology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana, India, between September 2020 to August 2021, is the site of this prospective, randomised, double-blind control trial. Following permission from the institutional review board, 50 patients aged 20-60 years old with ASA physical status grades I and II who were scheduled for upper limb procedures lasting less than 90 minutes were included.

Results: Regarding age, sex, weight, and operation time, there were no significant differences between the Groups. Compared to Group B's 5.270.58 minutes and 18.071.26 minutes for the beginning of sensory and motor block, Group A's 1.80.76 minutes is much shorter. Recovery times for sensation and movement in Group A were 18.873.27 minutes and 25.63.82 minutes, respectively, while in Group B those numbers were 4.80.7 minutes and 2.530.51 minutes. Group A had 1.770.43 cases of sedation, while Group B had 1. The average time for postoperative analgesia in Group A was 416.245.73 minutes, while in Group B, this number was just 11.330.96 minutes. There were no negative reactions.

Conclusion: With the addition of Dexmedetomidine 0.5 micrograms/kg to lignocaine for intravenous regional anaesthetic, the onset of sensory and motor blocking was accelerated, tourniquet pain was reduced, post-operative analgesia lasted longer, and hemodynamic stability was improved, all without adverse effects.