International Journal of Advanced Research in Medicine
2020, Vol. 2, Issue 2, Part D
Prediction of pregnancy induced hypertension by maternal serum βhCG levels in second trimester
Author(s): Madhuri S, Shyamala Devi S, Babulal S and Gayatri S
Background: There is no single test that is reliable and cost-effective for predicting pregnancy induced hypertension (PIH). It is hypothesized that during mid-trimester, immunological changes occur in the trophoblast resulting in secretory response which is seen as a rise in βhCG levels. An initial screening test like serum βhCG might help in categorizing patients who require special attention throughout pregnancy.
Methods: This is a prospective observational study conducted at Government General Hospital (GGH), Guntur, in the department of Obstetrics and Gynecology on 100 pregnant women in their second trimester (13-20 weeks) attending the outpatient department (OPD) from December 2020 to December 2021, who were followed up till term. Maternal serum βhCG levels were estimated.
Results: Twenty three women developed PIH and 77 remained normotensive. Out of the 23 cases, 20 cases showed elevated βhCG values in 13-20 weeks.
Conclusion: Elevation in maternal serum βhCG levels in early second trimester is a good non-invasive, reliable and economical test which can be used as a predictor of PIH before the clinical onset of the disease.
Madhuri S, Shyamala Devi S, Babulal S, Gayatri S. Prediction of pregnancy induced hypertension by maternal serum βhCG levels in second trimester. Int J Adv Res Med 2020;2(2):304-306. DOI: 10.22271/27069567.2020.v2.i2d.407