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International Journal of Advanced Research in Medicine
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International Journal of Advanced Research in Medicine

2020, Vol. 2, Issue 2, Part D

Prediction of pregnancy induced hypertension by maternal serum βhCG levels in second trimester


Author(s): Madhuri S, Shyamala Devi S, Babulal S and Gayatri S

Abstract:
Background: There is no single test that is reliable and cost-effective for predicting pregnancy induced hypertension (PIH). It is hypothesized that during mid-trimester, immunological changes occur in the trophoblast resulting in secretory response which is seen as a rise in βhCG levels. An initial screening test like serum βhCG might help in categorizing patients who require special attention throughout pregnancy.
Methods: This is a prospective observational study conducted at Government General Hospital (GGH), Guntur, in the department of Obstetrics and Gynecology on 100 pregnant women in their second trimester (13-20 weeks) attending the outpatient department (OPD) from December 2020 to December 2021, who were followed up till term. Maternal serum βhCG levels were estimated.
Results: Twenty three women developed PIH and 77 remained normotensive. Out of the 23 cases, 20 cases showed elevated βhCG values in 13-20 weeks.
Conclusion: Elevation in maternal serum βhCG levels in early second trimester is a good non-invasive, reliable and economical test which can be used as a predictor of PIH before the clinical onset of the disease.


DOI: 10.22271/27069567.2020.v2.i2d.407

Pages: 304-306 | Views: 32 | Downloads: 12

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How to cite this article:
Madhuri S, Shyamala Devi S, Babulal S, Gayatri S. Prediction of pregnancy induced hypertension by maternal serum βhCG levels in second trimester. Int J Adv Res Med 2020;2(2):304-306. DOI: 10.22271/27069567.2020.v2.i2d.407
International Journal of Advanced Research in Medicine