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International Journal of Advanced Research in Medicine
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International Journal of Advanced Research in Medicine

2020, Vol. 2, Issue 1, Part A

Characterization and drug sensitivity patterns of gram positive bacteria and fungus in blood stream infection


Author(s): Sriprasad Mohanty, Pranay Kumar Patro, Sudipti Sahu and Aditya Narayan Sahu

Abstract:
Back ground: Blood stream infections can lead to life threatening sepsis and require rapid antimicrobial treatment. The organisms implicated in these infections vary with the geographical alteration. Infections caused by MDR organisms are more likely to increase the risk of death in these patients. The present study was aimed to study the profile of gram positive bacteria and fungus causing bacteremia and understand drug resistance patterns in our hospital.
Materials and Methods: A total of 300 blood samples collected over a year from clinically suspected cases of bacteremia were studied. The isolates were identified by standard biochemical tests and antimicrobial resistance patterns were determined by CLSI guidelines.
Results: Positive blood cultures were obtained in 9.2% of cases of which Gram-positive bacteria accounted for 58.3% of cases with staph aureus predominance; and 1.5% were fungal isolates. The most sensitive drugs for Gram-positive isolates were vancomycin, teicoplanin, daptomycin, linezolid, and tigecycline.
Conclusions: The prevalence of MRSA and vancomycin resistance was 70.6% and 21.6%, respectively. ESBL prevalence was 39.6%. Overall low positive rates of blood culture were observed.
Key words: Blood Stream infections, Antibiotic Sensitivity, Antimicrobial resistance, Gram positive bacteria, Fungus


DOI: 10.22271/27069567.2020.v2.i1a.76

Pages: 50-55 | Views: 38 | Downloads: 17

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How to cite this article:
Sriprasad Mohanty, Pranay Kumar Patro, Sudipti Sahu, Aditya Narayan Sahu. Characterization and drug sensitivity patterns of gram positive bacteria and fungus in blood stream infection. Int J Adv Res Med 2020;2(1):50-55. DOI: 10.22271/27069567.2020.v2.i1a.76
International Journal of Advanced Research in Medicine