International Journal of Advanced Research in Medicine
2020, Vol. 2, Issue 1, Part A
A study on microvascular complications in patients with newly detected Diabetes Mellitus
Author(s): Mohan R, Manjunath Alur and SN Vishwakumar
Abstract:Introduction: Microvascular complications such as diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy are associated with considerable medical and economic impact among persons with diabetes. In the UK Prospective Diabetes Study [UKPDS], 37% of patients with newly diagnosed type 2 diabetes developed at least one microvascular complication over a ten years period.
Methodology: The procedure was told to the patients. 5.07 Simmes Weinstein monofilament consisted of a plastic handle supporting a nylon filament. The filament was placed perpendicular to the skin of the foot, and the pressure was applied until the filament buckles. The filament was held in place for approximately 1 second, then released. The patients were asked to elicit a ‘Yes/No’ response to monofilament pressure and correctly identify the site of contact. Inability to perceive the 10 g of force it applies was associated with clinically significant large fibre neuropathy. Like this 9 plantar sites and 1dorsal site were tested in each foot.
Results: Statistical analysis of above obtained data reveals that patient with HbA1c ≥8% have 4.4 times higher risk of developing microvascular complications than patient with HbA1c ≤8%. This indicates HbA1c is a better predictor of microvascular complications in diabetics. Most of the patients had normal Blood urea and Serum creatinine levels. 25 patients had urea > 40mg/dl. 2 patient had creatinine > 2mg/dl.
Conclusion: It is clear that significant increase in Blood urea and Serum creatinine levels which is indicative of renal involvement is less common at diagnosis of diabetes mellitus.
Mohan R, Manjunath Alur, SN Vishwakumar. A study on microvascular complications in patients with newly detected Diabetes Mellitus. Int J Adv Res Med 2020;2(1):22-25. DOI: 10.22271/27069567.2020.v2.i1a.34