Study to evaluate the correlation between various biochemical parameters (HbA1C, lipid profile and CRP) among type 2 diabetes mellitus patients
Author(s): Dr. Sunil Kumar Gulati
Abstract:Aim: The aim of this study to determine the relation between HbA1C, Lipid profile and CRP in individuals with type 2 diabetes mellitus.
Material and Methods: This prospective observational study was carried out in the Department of Medicine Metro Hospital and Cancer Research Centre, Jabalpur, MP India from July 2018 to February 2020. The patients above 30 years with fasting venous blood glucose value equal or more than 100 mg/dl and postprandial glucose >140 mg/dl were include in this study. FBS and PPBS, CRP (Immuno turbid metric method), and HbA1C (ion exchange chromatography using HPLC) lipid profile samples were drawn at entry and at subsequent follow-up with a minimum gap of 3-6 months.
Results: There was no significant difference between gender, age and BMI (p>0.05). FBS and HbA1C were directly correlated. PPBS showed a direct correlation with both HbA1C and CRP in this study. There was a significant positive correlation between CRP and total cholesterol (p<0.05). There was no significant correlation between CRP and LDL cholesterol (p>0.05). There was a negative correlation between HDL cholesterol and CRP. There was significant positive correlation between CRP and triglyceride levels (p<0.05). There was significant correlation between CRP and HbA1C (p<0.05).
Conclusion: We concluded that the CRP is an additional marker of better glycaemic control and also correlates with the dyslipidaemia profile seen in type 2 diabetes mellitus.
Dr. Sunil Kumar Gulati. Study to evaluate the correlation between various biochemical parameters (HbA1C, lipid profile and CRP) among type 2 diabetes mellitus patients. Int J Adv Res Med 2020;2(1):75-78. DOI: 10.22271/27069567.2020.v2.i1a.131