Investigating the impact of lipid profile on hypertension in overweight individuals
Author(s): Yaseen Khashman Hussein and Abdulhadi Mohamed Jumaa
Abstract: Background: Excess weight and obesity significantly contribute to hypertension and dyslipidemia, hence elevating the probability of cardiovascular illnesses. The correlation between lipid profile irregularities and hypertension in overweight individuals is a subject of continued investigation. The present research seeks to examine the correlation between lipid profile and hypertension in overweight individuals aged 20 to 24 years.
Objectives: The present research aimed to ascertain the relationship between lipid profile components (cholesterol, triglycerides, LDL, HDL) and hypertension in overweight persons, while also evaluating the prevalence of hypertension and dyslipidemia within this population.
Methodology: Ninety participants participated in the present investigation, comprising 55 overweight people, 20 healthy controls, and 15 obese individuals who were excluded. The research was carried out in the College of Medicine, Tikrit University, from February to May 2024. The eligibility criteria for participation were individuals classified as overweight (BMI < 30 kg/m²). The age of the research sample population varied from 20 to 24 years. Blood samples were obtained following a 24-hour fast, and lipid profiles (cholesterol, triglycerides, LDL, HDL, and VLDL) were assessed utilizing established biochemical methods. Statistical analysis was conducted utilizing SPSS version 23, with p-values below 0.05 being statistically significant.
Results: The findings indicated a substantial elevation in body weight, BMI, and blood pressure (systolic and diastolic) in overweight individuals relative to controls (p< 0.01). Among the 90 subjects, 61.1% of the total subjects (55 out of 90) are overweight. Among them, 30% suffer from hyperlipidemia, and 20% have elevated blood pressure, both systolic and diastolic. Hypertensive individuals demonstrated markedly elevated levels of total cholesterol (225.9±41.5 mg/dL), triglycerides (187.5±45.2 mg/dL), and LDL (141.5±42.2 mg/dL) in comparison to healthy controls (p< 0.01). Nonetheless, no substantial change was observed in HDL and VLDL levels between the two groups.
Conclusion: The research found a substantial correlation between obesity and hypertension, along with dyslipidemia. In overweight people, elevated cholesterol, triglycerides, and LDL levels correlated with heightened blood pressure. The deficiency of physical exercise was recognized as an element contributing to the prevalence of obesity and hypertension. It is recommended that overweight individuals engage in regular physical exercise and follow a healthy diet to manage their lipid profile and blood pressure.
DOI: 10.22271/27069567.2025.v7.i1a.599Pages: 09-13 | Views: 65 | Downloads: 20Download Full Article: Click Here
How to cite this article:
Yaseen Khashman Hussein, Abdulhadi Mohamed Jumaa.
Investigating the impact of lipid profile on hypertension in overweight individuals. Int J Adv Res Med 2025;7(1):09-13. DOI:
10.22271/27069567.2025.v7.i1a.599