The possible role of eradication of Helicobacter pylori infection on glycemic control in type 2 diabetes mellitus patients
Author(s): Mohamed Ahmed Fouad EL-said Badawy, Mohamed Abo Freikha, Hisham Ahmed Eissa Elserogy and Mohamed Sarhan
Abstract:Background: One of the most prevalent chronic infections in the world, Helicobacter pylori (H. pylori), is the primary contributing factor to gastritis, peptic ulcers, and stomach cancer. Chronic infections frequently have an impact on diabetic patients. Numerous studies have assessed the incidence of H. pylori infection in diabetes individuals and its potential impact on the way their metabolism is regulated. While some studies found no association between glycemic control and H. pylori infection, some identified a greater incidence of the infection in diabetes individuals and worse glycaemic control.
Aim and objectives: To investigate the impact treating Helicobacter pylori infection may have on individuals with type 2 diabetes mellitus' ability to maintain glycemic control.
Subjects and Methods: A 50-person type 2 diabetes mellitus randomised controlled trial was conducted at Tanta University Hospital's outpatient diabetes and endocrinology clinic. Each patient underwent a thorough clinical examination, extensive history taking, and investigations.
Result: Before and after, there was a high significant difference in FBG and a significant difference in HbA1C.
Conclusion: Finally, we found that the rate of H. pylori eradication with OCA or OMAB treatment is lower in patients with type 2 diabetes than in non-diabetics, and that H. pylori medication had no effect on glycemic control in people with type 2 DM.
Mohamed Ahmed Fouad EL-said Badawy, Mohamed Abo Freikha, Hisham Ahmed Eissa Elserogy, Mohamed Sarhan. The possible role of eradication of Helicobacter pylori infection on glycemic control in type 2 diabetes mellitus patients. Int J Adv Res Med 2023;5(2):38-42. DOI: 10.22271/27069567.2023.v5.i2a.477