International Journal of Advanced Research in Medicine
2021, Vol. 3, Issue 2, Part B
Case series of rhinocerebral mucormycosis second wave covid 2021: Mortality or survival real factors
Author(s): Sunil Kumar Sharma
Abstract: Background: Rhinocerebral mucormycosis is a complex and fatal infection typically affecting diabetic and/ or immunocompromised patients, but recently seen in large numbers during the second wave of corona infection. This dreadly infection was found typically in patients who were administered steroids and higher antibiotics. Usually, these kinds of manifestations are noticed due to inhalation of fungal spores. Fungi constitute a kingdom of ubiquitous eukaryotic organisms that actively replicate during decomposition and recycling of matter in the natural environment. About 50000 fungal species, of which only 400 are actually pathogenic for humans. Approximately a dozen of which are responsible for 90% of frequently encountered fungal infections. Material and methods: Survival rate of patients is moderately high 95% and Mortality rate is only 5% in our series due to early diagnosis and treatment with aggressive sugar control, repeated debridement antifungal therapy and regular follow up with MRI PNS Contrast. Results: In this case series, 156 cases with rhinocerebral mucormycosis were presented. The etiologic agents and other survival and Mortality factors of mucormycosis in 156 Patients were isolated and identified by sequence analysis and data were registered and presented. Conclusion: In patients with mucormycosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, MRI Contrast and control of risk factors like, Covid patient on steroids and higher antibiotics, diabetes mellitus are the main parameters of successful management of this lethal infection.