2021, Vol. 3, Issue 1, Part I

Materials and Methods: A prospective observational research was performed on 50 patients diagnosed with dengue fever at a tertiary care facility. This study was conducted at the Department of General Medicine, Surabhi Institute of Medical Sciences, Mundrai, Telangana, India from March 2020 to February 2021. Individuals with pre-existing diabetes were excluded. Blood glucose levels, HbA1c, and inflammatory markers were assessed before admission, throughout hospitalization, and during a follow-up visit after four weeks. A statistical study was conducted to ascertain the incidence and predictors of new-onset diabetes mellitus.

Results: Temporary hyperglycemia was experienced by twelve out of fifty patients, which is twenty-four percent, during the acute phase of dengue fever. When the follow-up was performed, there were six patients who met the criteria for newly diagnosed diabetes mellitus, which is twelve percent. A number of potential causes were identified, including insulin resistance, pancreatic involvement, and increased inflammatory markers. An increased prevalence of persistent hyperglycemia was seen in patients who had severe dengue.

Conclusion: A subset of dengue fever patients may develop new-onset diabetes as a result of the inflammatory response that impacts insulin dynamics and pancreatic function. For early discovery and management, it is critical to recognize this relationship. We need further research on dengue survivors to determine the metabolic consequences in the long run.