International Journal of Advanced Research in Medicine
2021, Vol. 3, Issue 1, Part B
Prediction of large esophageal varices in cases with cirrhosis of liver: A non-invasive approach
Author(s): Dr. R Venkat Naik and Dr. Chandulal
Abstract: Esophageal variceal bleeding is a severe lethal complication of cirrhosis due to its high rate of mortality. Non-invasive procedures like clinical, biochemical and USG have immense predictive value in the diagnosis of esophageal varices. The present study was designed to evaluate non-invasive predictors for esophageal varices. A total of 100 clinically diagnosed cases with cirrhosis of liver were recruited. Laboratory parameters like serum bilirubin, serum albumin, platelet count and prothrombin time, Clinical parameters like child Pugh class, ascites and splenomegaly and USG parameters like portal vein and spleen diameter along with echo texture of the liver, spleen size and direction of blood flow, portal vein diameter and platelet count/spleen diameter ratio was determined. Among the study cases, 57% cases had small (Grade I-II) varices and 43% cases had large varices (Grade III-IV). Alcohol was the most common etiology in 48.8% cases with large varices and 28% cases with small varices, followed by HBV. In large varices group, 55.8% were in CTP-C, 27.9% were in CTP-B and 16.2% were belonged to CTP-A. The Grade III-IV large esophageal varices were significantly correlated with the total bilirubin levels, low albumin levels, elevated prothrombin time, increased portal vein diameter, increasing spleen size, low platelet count, lower values of platelet count and spleen diameter ratio. The above parameters are the significant predictors of large esophageal varices.
Dr. R Venkat Naik, Dr. Chandulal. Prediction of large esophageal varices in cases with cirrhosis of liver: A non-invasive approach. Int J Adv Res Med 2021;3(1):99-102. DOI: 10.22271/27069567.2021.v3.i1b.111