Diabetic pulmonary tuberculosis and its impact on clinical and radiological manifestations in individuals with diabetes mellitus: a cross-sectional study
Author(s): Dr. M Phanindranath Reddy and Dr. Avala Ravi Charan
Abstract: Introduction: Tuberculosis continues to be a significant source of illness and mortality globally. Approximately one-third of the global population is infected, and the incidence of tuberculosis has been increasing worldwide in recent years. To investigate the impact of glycemic management on the radiographic manifestation of pulmonary tuberculosis in individuals with diabetes.
Materials and methods: It is a prospective cross-sectional study. Patients over 18 years with Pulmonary Tuberculosis and Diabetes Mellitus were included. Pulmonary tuberculosis was excluded in conjunction with other immunocompromised illnesses such as HIV, chronic renal disease, malignancy, long-term steroid use, and immunosuppressive medications. This research was performed in the Department of Pulmonology, Madha Medical College, Mangadu, Thandalam, Tamil Nadu, from March 2018 to February 2019.
Results: Among 200 tuberculosis patients, 88 were diabetic, resulting in an incidence of 44%. The average age was 52.13 ± 10.93 years; 52% were male, the mean HbA1C was 9.04 ± 1.70, and 93.2% exhibited uncontrolled glycemic state.Seventy-eight individuals had lower lung field abnormalities, with a mean HbA1C of 8.87. Thirty-nine individuals (29.5%) presented with upper lung field abnormalities, having a HbA1C of 9.25, while 11.3% demonstrated abnormalities in both lung fields, with a HbA1C of 9.36. One hundred eight individuals had nodular infiltrative lesions, and eighteen had cavities, with a HbA1C of 9.88. Furthermore, 83.3% of those with cavities were located in the lower lung fields.
Conclusion: Atypical radiographic manifestations of lower lung field involvement are more prevalent in patients with diabetes. Patients with inadequate glycaemic management had a higher prevalence of cavitary lesions compared to their counterparts, although this had no significant impact on the zonal distribution of the radiographic lesions
DOI: 10.22271/27069567.2019.v1.i1a.574Pages: 112-115 | Views: 130 | Downloads: 21Download Full Article: Click Here
How to cite this article:
Dr. M Phanindranath Reddy, Dr. Avala Ravi Charan.
Diabetic pulmonary tuberculosis and its impact on clinical and radiological manifestations in individuals with diabetes mellitus: a cross-sectional study. Int J Adv Res Med 2019;1(1):112-115. DOI:
10.22271/27069567.2019.v1.i1a.574