A cross-sectional study to determine the lipid profile derangement in newly diagnosed type-2 diabetic patients
Author(s): Dr. P Hanumantha Rao and Dr. G Murali Mohan Reddy
Abstract:Aim: To study the lipid profile abnormalities in newly diagnosed type 2 diabetics.Methodology: A cross-sectional study was carried out to determine the triglyceride levels in newly diagnosed type 2 diabetic patients. A total of 200 newly diagnosed type 2 diabetics were enrolled in our study. Relevant patient data was collected from the inpatient and outpatient Department of General Medicine, Mamatha Medical College, Telangana, Khammam, India. Fasting lipid profile levels were measured in these patients. The Study was carried out during a period of 1 year. Inclusion criteria: All patients of age > 25 years who have been diagnosed as having type 2 diabetes mellitus within the last 3 months using the ADA (American Diabetes Association) criteria. All individuals signed informed written consent for their participation. Blood samples were taken of all the patients to analyze lipid profile and Blood glucose levels.Results: Out of 200 enrolled patients, the maximum number of patients belonged to the age group of 41-50 years (50%) and the least number belonged to the age group 20-30 years (1.5%). The gender distribution of the participants showed that 98 (49%) were males, and 102 (51%) were females. According to ATP III classification, 88 (44%) participants had normal serum triglycerides levels which is level of serum triglycerides. Among the 112 participants with abnormal triglycerides, 32.5% had borderline high levels (150-199mg/dl), 19% had high levels (200-499 mg/dl) and 4.5% participants had very high triglycerides (≥500 mg/dl). According to the NCEP ATP III criteria, HDL levels ≤40 is considered low for males and ≤50 is considered low for females. Based on this criterion, in our study, 48.5% participants had low HDL and 51.5% participants had normal HDL. 60 (30%) participants had an optimal level of LDL, 79 (39.5%) had near optimal levels of LDL, 40 (20%) had borderline high levels of LDL, 16 (8%) had high levels of LDL, and 5 (2.5%) participants had very high levels of LDL. 137 (68.5%) participants had desirable total Cholesterol levels of < 200mg/dl, 60 (30%) had borderline high levels of 200- 239mg/dl and 3 (1.5%) had high total cholesterol levels of ≥240mg/dl. Conclusion: This study found that lipid profile is associated with T2DM. Hence in view of the associated cardiovascular mortality and morbidity, optimum care of these patients include not only adequate glycemic control but effective measure to control the dyslipidemia as well. The appropriate treatment for glycemic control should go concomitantly with lipid lowering drugs and lifestyle modifications.
Dr. P Hanumantha Rao, Dr. G Murali Mohan Reddy. A cross-sectional study to determine the lipid profile derangement in newly diagnosed type-2 diabetic patients. Int J Adv Res Med 2019;1(1):49-52. DOI: 10.22271/27069567.2019.v1.i1a.339